• What are the new approaches and strategies to reduce maternal mortality, and prevent deaths of newborns and children under 5 years of age? What are the effective ways for reducing neonatal mortality in particular? How do we prevent accident deaths?
  • How can societies realize sexual and reproductive health and rights and rapidly reduce fertility rates to replacement level or below through exclusively voluntary means?
  • How can the world end the epidemics of AIDS, tuberculosis, malaria and neglected tropical diseases and combat hepatitis, water-borne diseases and other communicable diseases by 2030?
  • What are effective ways of reducing premature mortality from non-communicable diseases through prevention and treatment?
  • What can be done to reduce the burden of and promote mental health and well-being?
  • How can we strengthen the prevention and treatment of substance abuse, including narcotic drug abuse and harmful use of alcohol?
  • How can we ensure universal access to sexual and reproductive health-care services, including for family planning, information and education, and the integration of reproductive health into national strategies and programmes?
  • What are the lessons learned from the global experience of promoting universal health coverage, including financial risk protection, access to quality essential health-care services and access to safe, effective, quality and affordable essential medicines and vaccines for all?
  • How can we substantially reduce the number of deaths and illnesses from hazardous chemicals and air, water and soil pollution and contamination?
  • What do we know about ways to support the research and development of vaccines and medicines for the communicable and non-communicable diseases that primarily affect developing countries, provide access to affordable essential medicines and vaccines and, in particular, provide access to medicines for all?
  • What are the strategies to substantially increase health financing and the recruitment, development, training and retention of the health workforce?